there is no need to discuss locking vs spinning, you dont' have a choice in the matter and should follow the transmission manufacturer instructions. In most cases, they recommend you lock the shaft and obviously you also need to follow the instructions of the dripless seals manufacturer, if equipped.
Putting the engine in gear usually doens't not work since most inboard trannies are hydraulic and with the engine off there is no pressure for the clutch to engage. check that before assuming that you are locked!
these issues aside, i'm still not sure that you really gain a lot by running on one engine jsut to save fuel... if it takes X hp to push the boat at Y speed, whether or not the hp comes from one or two engine makes little difference and whatever you win by eliminating losses due to friction, heat, etc... you probably loose it by the locked or spinning prop.
Not worth it. if you're concerned about fuel, then slow down half a knot.
also, twin engine boats are propped for twin operation. if you try to run a little too fast on one engine, maybe just by 1kt, that engine could be slightly overloaded increasing wear...
now, just like any multi engine pilot trains for operation with an engine out, boat owners with twin should practice running on one engine once in a while (docking, turning, etc...) instead of relying on that red or yellow card they carry!
